Nuclear actin: to polymerize or not to polymerize

Nuclear actin: to polymerize or not to polymerize

The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between actin form and function in the cytoplasm implies that understanding the structural properties of nuclear actin is elementary to fully understanding its function. In this ...

actin: to polymerize or not to polymerize

© The Rockefeller University Press $8.00 The Journal of Cell Biology, Vol. 172, No. 4, February 13, 2006 495–496 http://www.jcb.org/cgi/doi/10.1083/jcb.200601095 JCB 495 The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between ...

Polymerize it all! A critical review

Introduction Polymerases are fascinating and ubiquitous enzymes that catalyse the synthesis of nucleic acids with impressive rates and fidelity. Indeed, polymerases are capable of distinguishing minute differences in nucleoside triphosphates (e.g. the 2'OH residue that is absent in dNTPs but present in rNTPs) and process with very low error rates (~106 for Pfu DNA polymerase, e.g.). However, th...

Folic Acid Supplementation: to Advise or not to Advise?

Approaches of Islamic Ideology to interfere or not to interfere in the area of divergence

  Introduction: The principles of the School of Natural Rights during the Age of Entitlement, i.e., the 17th and 18th centuries, regarding the centrality of human being, his freedom and self-determination, as well as the human rights recommendations and documentations designed and drafted by the international organizations during the current century and the appearance of “globalization”, the...